Diosmin is a molecule of plant origin present mainly in citrus fruits, but also in Barosma betulina and Ruta graveolens. In particular, it is a bioflavonoid. In addition to being an ingredient in supplements to be taken orally, it is also found on the market in topical products, such as creams or gels to be applied directly to the area to be treated. Diosmin is mainly proposed to treat hemorrhoids by virtue of its supposed anti-inflammatory properties. It is also suggested to take it to promote the correct functionality of the veins, for example in the case of varicose veins, venous stasis in the lower limbs and gingival or eye bleeding. In some cases it is also proposed to reduce lymphedema associated with surgery for the removal of breast tumors and to avoid toxic effects on the liver.