• Latin Name: Linum Usitatissimum
  • CAS No.: 8001-26-1
  • Active Ingredient: Flax Lignans Lignans, SDG Secoisolariciresinol Diglycoside
  • Specifications: ?25%
  • Test Method: HPLC


Secoisolariciresinol Diglycoside, or SDG,  is a plant lignan most notable found in flaxseed (linseed). SDG is classified as a phytoestrogen sice it is a plant-derived, nonsteroid compound that possesses estrogen-like activity.

Lignans are one of the two major classes of phytoestrogens; the other class is the isoflavones. Most of the effects of oral SDG are mediated by enterolactone and enterodiol.


SDG has estrogenic and antioxidant activities. It may also have antiestrogenic, anticacinogenic, antiatherogenic and antidiabetic activities.

Research suggest lignans may benefit consumers in the following areas:  

  • Prostate health
  • Bone health
  • Breast health
  • Reducing symptoms of menopause
  • Heart health
  • Hair loss
  • Acne
  • Inflammation

Metabolism and mechanism of lignans:

Lignans are natural compounds with two or three molecules of benzene propyl’s combination by various modalities. Being phytoestrogen, flax lignans can bind estrogen receptors and interfere hormone metabolism as soya isoflavones and red clover isoflavones. Them main ingrediatn of flax lignans is called SDG. SDG is the precursor of mammal lignans because it is converted into entrolactone (EL) and enterodiol (ED) after ingestion.